Liv 52 analogues are cheaper. "Liv.52": reviews of doctors and instructions for use

Medicine for the liver Liv 52 is a combined herbal preparation with a choleretic and hepatoprotective effect. Its use improves the processes of digestion and assimilation of food, supports liver function and promotes the restoration of liver cells (hepatocytes).

Liv 52 for the liver: description, principle of action

The therapeutic properties of the drug are due to the influence of natural extracts medicinal plants contained in its composition. Liv 52 has antioxidant, hepatoprotective, anti-inflammatory, choleretic and antitoxic effects. The active substances included in its composition have membrane-stabilizing properties, accelerate the processes of regeneration, recovery of hepatocytes, stimulate the production of specific proteins and phospholipids, accelerate intracellular metabolism and thereby prevent fibrotic, fatty and other degenerative changes in the liver.

Regular intake of the drug can reduce the level of bilirubin and alkaline phosphatase to normal values, improve the composition and properties of bile and prevent the formation of gallstones. Liv 52 is often prescribed for alcoholic liver damage, as the drug reduces the level of ethanol in the urine and blood and accelerates the excretion of toxic decay products from the body. These properties help to prevent damage to hepatocytes and reduce the severity of the "hangover syndrome".

Composition and forms of release

The drug Liv 52 is produced in the form of tablets and drops. The composition of these forms has slight differences.

Tablets Liv 52 gray-green color, round shape. May have small blemishes. Each of them contains:

dry extract of chicory;
nightshade powder;
caper root (powder);
terminalia bark (powder);
yarrow seeds;
tamarix powder;
iron oxide.

The main composition of the drug is supplemented with a mixture of extracts from medicinal raw materials (fumes, emblics, radishes, terminalia, embelias, etc.), which are specially processed over steam. Tablets are packaged in 100 pieces in a plastic bottle and cardboard packs.

Drops Liv 52 - dark liquid Brown. They consist of the same mixture of main components: chicory, capers, nightshade, tamarix, yarrow. But these ingredients are presented in liquid form and their dosage is several times less than in the tablet version of the drug. Plant extracts are dissolved in a water base and supplemented with peach flavor. Drops are released in dark glass bottles with a volume of 60 ml, equipped with a pipette for easy dosing.

When is Liv 52 used?

Treatment of the liver with Liv 52 is carried out in order to protect hepatocytes from negative external influences, accelerate the processes of regeneration and restoration of liver cells. According to the instructions, the phytopreparation is indicated for use in the following conditions:

acute and chronic hepatitis (alcoholic, infectious, medicinal);
(fatty degeneration of the liver);
concomitant lesions of the biliary tract and gallbladder (dyskinesia, cholecystitis, cholecystocholangitis).

In addition, Liv 52 is prescribed for anorexia, for the purpose of prevention when taking certain medications with hepatotoxic effects (hormones, antibiotics, antitumor agents), as well as to maintain the liver after a course of radiation therapy.

The drug does a good job of removing toxic compounds, alcohol breakdown products and other harmful substances from the body that negatively affect the functions of an important organ. Additionally, the drug eliminates congestion in the biliary tract, which allows you to normalize the digestive process and improve the general condition of the patient.

Due to its therapeutic properties, Leaf 52 has found application in bodybuilding. Athletes use it to maintain liver function during hormonal and drug stimulation of muscle growth.

Instructions for using the medicine

If Liv 52 is used for prevention purposes, it is enough to take 1-2 tablets of the herbal remedy in the morning and evening. For therapeutic purposes, the dosage of the drug is different and is determined by the doctor, taking into account the severity of the condition and other individual characteristics of the patient.

The standard treatment regimen for adults is a stock dose of 4-9 Liv 52 tablets, which are divided into two to three doses. The dosage of drops for adults is 1-2 teaspoons, they are taken twice a day.

There are very few contraindications to the use of Liv 52. This is an individual intolerance to its components, the period of pregnancy and lactation. With extreme caution, the herbal remedy is used in patients with gastrointestinal diseases during exacerbations.

The drug in the form of tablets is not prescribed for children under 5 years of age, while Liv-52 in the form of drops can be used with therapeutic and preventive purpose in children from 2 years of age. Liv 52 drops do not contain ethyl alcohol, therefore they are suitable for the treatment of children with diseases of the biliary tract and liver.

In addition, before taking the medicine, you should pay attention that in combination with Ibuprofen, Liv 52 reduces its therapeutic effect. And the appointment of the drug simultaneously with antibiotics of the tetracycline group reduces the effectiveness and bioavailability of the latter.

When taking a hepatoprotective agent, alcohol should be completely excluded, otherwise the therapeutic effect of taking Lif 52 will be reduced to zero.

Adverse reactions

The use of herbal medicine can provoke hypersensitivity reactions in patients prone to allergies. On the part of the skin, the appearance of rashes, itching, swelling and hyperemia is noted. In exceptional cases, symptoms of epidermal toxic necrolysis develop.

Dyspeptic symptoms may occur: nausea, loose stools, abdominal discomfort. If any adverse reactions occur, the drug should be discontinued and a doctor should be consulted to adjust the subsequent treatment regimen.

Liv 52 analogues

Phytopreparation Liv 52 has a unique composition, which is based on a well-chosen complex of plant extracts. Therefore, this drug does not have structural analogues containing the same components. If necessary (for example, if an allergy occurs), the doctor can choose another remedy with a similar therapeutic effect from an extensive list of hepatoprotective drugs. You can replace Lif 52 with the following medicines:

Gepamerz;
Heptral;
Gepabene;
Karsil Forte;
Legalon;
Silymarin;
Sirepar;
Tykveol;
Ursosan;
Essentiale Forte;
Essliver.

The attending physician should select the appropriate version of the analogue, who will take into account possible contraindications, the presence of concomitant diseases, and other nuances.

The cost of the drug

The price of the drug for the liver Liv 52 depends on the form of release and the cheating of pharmacy chains. So, the cost of a package with Liv 52 tablets (100 pieces) ranges from 230 to 300 rubles. Liv 52 in drops costs on average from 280 rubles per bottle.

The price of the drug is quite acceptable, compared with other medicines for liver restoration (for example, essential phospholipids), the course of treatment will be much cheaper. The drug Liv 52 is released from pharmacies without a doctor's prescription, but before buying and using this product, a specialist consultation is necessary.

Liv 52 is available in drops and tablets for oral administration.

Registration number:

P N014783/01-040310

Trade name: Liv.52®

Dosage form Tablets.

Nosological classification (ICD-10)

B19 Viral hepatitis, unspecified
K71 Liver toxicity
K73 Chronic hepatitis, not elsewhere classified
K74 Fibrosis and cirrhosis of the liver
K76.0 Fatty liver, not elsewhere classified
K76.9 Liver disease, unspecified
R63.0 Anorexia

Pharmacological group

The drug improves digestion and absorption of food. It increases the content of vitamin E in hepatocytes and CYP450, activates the formation of proteins and phospholipids. The drug restores hepatocytes, improves intracellular metabolism, normalizes the ratio of albumin and globulin, the level of liver enzymes, cholesterol and triglycerides. Reduces the level of bilirubin and alkaline phosphatase. Against the background of therapy, the ability of the liver to accumulate glycogen, the contractile function of the gallbladder improves.

The drug reduces the likelihood of gallstone formation, stimulates hematopoiesis. With alcoholic liver damage, the drug reduces the content of ethyl alcohol in the blood and urine. It increases the activity of acetaldehyde dehydrogenase, as a result, the concentration of acetaldehyde decreases, and it does not bind to proteins and is more quickly excreted from the body. The damaging effect of acetaldehyde on hepatocytes is reduced and the likelihood of a “hangover” syndrome, which is characterized by trembling of the limbs, nausea, vomiting, and headaches, is reduced.

Description and composition

The drug is available in round biconvex greenish-gray tablets with splashes.

The drops are a dark brown liquid.

The active substances are the following components:

capers are prickly;
common chicory;
nightshade black;
iron oxide;
cassia western;
kukubha;
yarrow;
Tamarix Gallic;
bringaraja;
phyllanthus niruri;
berhavia sprawling;
tinospora cordifolia;
garden radish;
amla;
chitrak;
currant embelia;
terminalia chebula;
wild rue.

As additional components, the tablets contain MCC, E 572, croscarmellose sodium and carboxymethylcellulose.

Auxiliary components of drops are:

sucrose;
peach fragrance;
purified water;
E331;
E 218;
E 216.

The mechanism of action of the hepatoprotector LIV 52

This hepatoprotector is a combined preparation based on plant components, due to which its action is determined. So, the composition of grassy capers contains:

ascorbic acid;
steroidal saponins;
thioglycosides;
routine;
quartzetin.

Thanks to this component, the drug LIV 52 has the following effects on the body:

painkiller;
diuretic;
hepatostimulating and hepatoprotective;
helps improve appetite.

The composition of wild chicory is represented by such components as:

fructose;
glycosides;
B vitamins;
choline;
ascorbic acid.

This component of the hepatoprotector LIV 52 contributes to:

improving the work of organs gastrointestinal tract;
increased appetite;
has a diuretic effect;
stimulates the production of bile.

The composition of black nightshade is represented by such components as:

glycoalkaloids;
citric and ascorbic acids;
tannins;
routine;
sitosterol;
asparagine;
saponins.

This component provides the following actions of the drug:

hepatoprotective;
painkiller;
emollient;
antispasmodic;
anti-inflammatory;
diuretic.

Cassia occidentalis contains organic acids, anthraglycosides, sterols and flavonoids. It has a laxative, choleretic and antitoxic effect on the body. Normalizes the process of bile discharge into the intestines. Doesn't disrupt work small intestine, has a tonic effect on the organs of the gastrointestinal tract, does not cause constipation.

Terminal arjuna is characterized by a general tonic and diuretic property, and tamarix kalsky has a hepatoprotective effect. The composition of the common yarrow includes vitamin K, flavonoids, essential oil and tannins. Therefore, it contributes to the expansion of the bile ducts and the intensification of the processes of bile secretion, reduces the severity of pain in the intestines, has a carminative effect and tones the function of the gastrointestinal tract. These properties allow the use of a hepatoprotector for peptic ulcers, gastritis, flatulence, kidney and liver diseases, and spastic ulcerative colitis.

Under the influence of iron oxide, the processes of hematopoiesis are intensified. In general, the drug has a choleretic, anti-inflammatory, hepatoprotective and antitoxic effect on the body. Against the background of its use, an improvement in the digestion process is noted, it stimulates hematopoiesis. The hepatoprotective effect is due to the membrane-stabilizing and antioxidant properties of the components that make up the drug.

In patients taking LIV 52, there is a decrease in the rate of degradation of cell membranes, an increase in the concentration of antioxidants in hepatocytes, the drug prevents the formation of free radicals.

The antitoxic property of the drug allows you to protect the endoplasmic reticulum of hepatocytes. Under the influence of LIV 52, normalization and an increase in the concentration of cytochrome P450 are noted. In patients with chronic alcoholism, the drug prevents lipid infiltration into liver cells. Protects the body from carbon tetrachloride. Helps slow down the development of the disease in the precirrhotic phase, protects the liver from further destruction.

While taking LIV 52, there is an increase in the production of protein, phospholipids and cholesterol, regeneration of liver cells, restoration of their functional ability. The hepatoprotector helps to improve appetite, makes it easier for gases to pass from the intestines. In malnourished patients, it increases body weight, including through the growth of bones and muscles. The combination of the components of the drug allows it to have an effective complex effect.

What helps Liv-52? As a hepatoprotector, the drug protects hepatocytes from damage and promotes their active regeneration. In addition, Liv-52 increases the activity of the biosynthetic function of liver cells, inhibits the oxidation of lipid components, protecting cell membranes from negative impact oxidation products on them. The action of the drug is also aimed at binding toxins and other harmful substances that have entered the body and adversely affect the function of hepatocytes. The drug Liv-52 successfully fights congestion in the biliary tract, eliminating the effects of dyskinesia and normalizing the digestive process, increasing the patient's appetite. To the above properties of the drug, you can also add a choleretic, antioxidant and mild diuretic effect.

The main indications for the use of Liv-52:

Diffuse liver damage (prevention and treatment);
Toxic lesions of hepatocytes;
Fatty degeneration of the liver;
Hepatitis of various origins;
Prevention of liver damage during the period of taking chemically aggressive medicines, for example, antitumor, antibiotics, etc.;
Prevention of liver damage during radiological treatment (irradiation);
Dyskinesia of bile ducts;
Cholecystitis, cholecystocholangitis;
Paraproteinemia (presence of functionally defective proteins in the blood);
Anorexia, weight loss in children.

Treatment of other gastrointestinal diseases

Liv 52 is used not only for liver pathologies, but also for diseases of other organs of the digestive system:

Very often this medicine is prescribed after removal of the gallbladder, but you should find out how effective its use is after cholecystectomy. After removal of the gallbladder, bile has nowhere to accumulate and it flows directly from the liver to the intestines. But in some cases, especially if the diet is not followed, bile can accumulate in the liver and cause inflammation.

That is why many patients after cholecystectomy complain of pain in the right hypochondrium. To support the activity of the liver, hepatoprotectors and cholagogues are prescribed. But Liv 52 is not the most effective in this situation - its action is more aimed at reducing the gallbladder, and since there is nothing to reduce after the operation, then its intake is not mandatory.

After cholecystectomy, drugs containing bile and bile acids are considered the most effective. Although it is worth saying that patient reviews speak of the effectiveness of Liv 52.

So, Igor writes: “After the removal of the gallbladder, pain periodically occurs under the right rib. The doctor advised taking courses of Hofitol or Liv 52. I tried both drugs, it seems to me that Liv 52 gives a positive result faster.”

Reception Liv 52 can be prescribed in violation of the pancreas. This drug or other choleretic agents are needed when bile is thrown into the pancreatic duct, causing it to become inflamed.

In addition, pancreatitis is often accompanied by diseases such as cholecystitis, biliary dyskinesia, cholangitis, so it is necessary to take medications that normalize the outflow of bile. Liv 52 is prescribed for pancreatitis to relieve the burden on the pancreas, eliminate bile stasis, prevent swelling and normalize digestion. But there are contraindications to taking the drug for such diseases:

acute pancreatitis;
stones in the gallbladder or ducts;
ulcerative colitis;
severe form of cirrhosis. Liv 52 is the most popular for pancreatitis due to its natural composition, as it is best tolerated and causes virtually no side effects. So, Maria writes: “I have had pancreatitis and cholecystitis for several years now, I take Liv 52 two courses a year. The attacks have practically disappeared, but of course, you need to maintain a diet, otherwise there will be no sense in the treatment.

With biliary dyskinesia, hepatoprotectors are prescribed for severe stagnation of bile or the cessation of its release. Liv 52 is one of the drugs that effectively fights cholestasis, eliminates the symptoms of dyskinesia and normalizes the functioning of the digestive organs.
Many patients noted that taking the drug during an attack eliminated pain. But Liv 52 is a non-specific drug in the treatment of this disease, as well as pancreatitis - in these diseases, the most important thing is to maintain a diet and refuse bad habits.
Valeria writes: “I have been taking Liv 52 for dyskinesia for two weeks and have already noticed that not only the discomfort in the abdomen has disappeared, but also the general condition has improved - the stool has returned to normal, the skin color has improved, heartburn has disappeared.”

The use of Liv-52 in the past and now

Liv-52 is a drug well known to domestic consumers. In the modern world, it was proposed for the treatment of viral hepatitis in 1955. The history of the use of Liv-52 in the Soviet, and then Russian practice of treating diseases accompanied by liver damage, has at least 40 years. In the US, the drug is not allowed to be sold as a medicine.

On the other hand, the latest studies, conducted according to the canons of evidence-based medicine, do not find confirmation of the effectiveness of the drug and sometimes even demonstrate its danger.

Since the invention, the drug has undergone a kind of rebranding - if initially in the instructions for use Liv-52 was positioned as a classic hepatoprotector capable of completely or almost completely restoring damaged liver tissue, now they talk about it mainly as a choleretic drug.

Apparently, this is due to the complex composition of the drug and the poor knowledge of its mechanism of action, the difficulty in conducting and interpreting the results of clinical trials. However, in this regard, it does not differ from other hepatoprotectors of plant origin: in order to figure out exactly how and from what exactly they help, people have yet to study and research them.

Instructions for use

Despite the natural composition of the drug, Liv 52 can only be prescribed by the attending physician, in order to avoid complications. There is a specific list of conditions for which this drug can help:

Liv 52 is actively prescribed after long-term treatment with antibiotics, cytostatics, sulfonamides and chemotherapy drugs to avoid drug intoxication. The drug is in demand among professional athletes - Liv 52 supports the activity of the liver when taking steroids.

The medicine has practically no contraindications for taking, more precisely, there are only four of them:

Pregnancy at any time.
lactation period.
Hypersensitivity to any component of the drug.
Age restrictions: drops can be from 2 years old, and tablets from 6 years of age.

If you compare the instructions for tablets and drops, you can see that they have an almost identical composition, only the doses of each active substance are several times less than in tablet form. If we compare Liv 52 tablets and capsules, they have an equal content of active ingredients, but the difference is that the capsules are absorbed much better, which is why they are prescribed to patients with gastrointestinal diseases.

The instructions for use indicate that the drug can be taken at any time, regardless of food intake. But experts recommend drinking the medicine half an hour before or after meals in order to achieve better absorption.

How to use:

IN childhood from 6 years old take 1-2 tablets or capsules 3 times a day for medicinal purposes and 2 times a day as a preventive measure.
Adults are prescribed 2-3 tablets or capsules 3 times a day.
From 2 years of age, 11 to 20 drops of the solution are prescribed 2 times a day.
Adolescents and adults can be prescribed from 20 to 160 drops 2 times a day.

The duration of treatment for acute hepatitis is 3 months, for chronic hepatitis - 6 months, for alcoholic destruction of the liver from six months to 12 months. Liv 52 is prescribed with extreme caution to patients with pathologies of the digestive system in the acute stage. If necessary, taking the drug, it is prescribed in the minimum dosage.

How to take the drug in the form of drops?

The drug in the form of drops is taken for prophylactic and therapeutic purposes. Children from 2 years old are recommended to take 11-20 drops twice a day, adults - 82-160 drops (1 or 2 teaspoons) twice a day.

children

For therapeutic purposes, children from 6 years of age take Liv 52 1-2 tablets three times a day.

For therapeutic or prophylactic purposes, children from 2 years of age take Liv 52 K, 11-20 drops twice a day.

During pregnancy and lactation

The drug is contraindicated for use during these periods.

Interaction with other medicines

Before starting treatment with Liv-52, you must carefully read the instructions for its use in order to prevent adverse events in the form of adverse reactions of the body to this drug. You should pay attention to the following factors:

The combination of Liv-52 with ibuprofen reduces the therapeutic effect of the latter;
The use of the drug together with antibiotics of the tetracycline group reduces their effectiveness;
During the course of treatment is not recommended to drink alcohol.

What form of the drug is most effective?

The most effective form of the drug is capsules. However, each has its own purpose. So, for people with diseases of the gastrointestinal tract (GIT), Liv 52 capsules are better suited, due to the fact that they help patients to better absorb the medicine.

Is the drug safe?

Experiments conducted in India have shown that this medicine helps protect the liver of rats from alcohol damage, and also improves liver function in acute viral hepatitis.

However, a group of European scientists conducted a study in 1997, the results of which are not encouraging. They treated half of their patients with alcoholic hepatitis with Liv-52 (given 1200 mg), and the rest of the patients were given a placebo. By the end of the experiment, among those who received a placebo, 86% of patients survived. And among those who received Liv-52 - only 74%.

Even worse was the case with the treatment of hepatitis C. During the treatment, 22 of the 23 patients who received Liv-52 died. All of these cases were associated with liver failure or bleeding. Whereas in the control group (who did not receive Liv-52) died less people: 3 out of 11.

From these studies, it can be concluded that in pre-existing liver diseases, this herbal remedy can further aggravate the situation. After the publication of the results of these experiments, Liv-52 was withdrawn from the drug market in the United States, although it can still be bought in this country as a dietary supplement.

Contraindications

Allergy to the components of the drug.
Pregnancy.
Diseases of the biliary tract.
Acute forms of bowel disease.
Diseases of the stomach.
Individual intolerance to the components of the drug.

Side effects

With moderate use, no side effects were found, however, with prolonged use, allergic reactions and dyspepsia may occur.

Overdose

There were no cases of overdose with the use of the drug. However, there is a possibility of manifestation of various allergic reactions with prolonged use of Liv 52 in large quantities.

Analogues

At the moment, there are no analogues of the agent for structural components, however, there are many analogues for the pharmacological group. For example, Holenzim. Most of them are also made from natural raw materials and have a lot of positive feedback. In this case, only the price plays a role. At the same time, Liv 52 is inferior in this indicator to many of its counterparts. Here is just a small list of the most famous of them:

Karsil;
Ovesol;
Hofitol;
Heptor;
Silymarin;
Galsten;
Flamin;
Urdox;
Phosfonciale;
Laennec;
Phosphogliv;
Essliver Forte;
Rezalut Pro;
Essentiale;
Livodexa;
Hepabene;
Ursosan;
Ursofalk;
Geptral;
Holenzim.

LIV 52 drug and alcohol

To some people, this hepatoprotector is known as a remedy that helps prevent the onset of hangover symptoms. Despite the fact that there have been quite a few clinical trials on humans, experiments on laboratory animals confirm the fact that during alcoholic liver damage, the components of this hepatoprotector prevent an increase in the activity of enzymes that destroy working liver cells. As a result, the load on this organ is significantly reduced, glutathione reserves are maintained, and lipid peroxidation is inhibited. Thus, LIV 52 protects the liver from alcoholic oxidative stress.

There is evidence that this hepatoprotector disrupts the binding of acetaldehyde, which is the main toxic breakdown product of alcoholic beverages in the human body, with hepatocyte proteins, which ensures its faster excretion from the body. An increase in the content of acetaldehyde in the urine was noted both in laboratory animals and in humans taking LIV 52.

A number of studies involving volunteers confirm the fact that the hepatoprotector has positive effect, which manifests itself in the form of an improvement in the patient's well-being, a decrease in the intensity of the severity of hangover symptoms, including during multi-day drinking bouts.

Although LIV 52 does not have any significant effect during a hangover, in the absence of contraindications, it can be used in combination with other drugs and means to prevent the onset of hangover symptoms and protect the body from the harmful effects of alcoholic beverages. Before taking the drug (both as part of a complex and as an independent remedy), it is necessary to consult a doctor to confirm that there are no contraindications to its use.

special instructions

Be wary appoint patients with acute diseases of the stomach and intestines.

Liv 52 in bodybuilding

The drug is often used in bodybuilding as a hepatoprotector for long-term courses of drug and hormonal stimulation of muscle growth and athletic performance.

Terms and conditions of storage

Store in a dry place out of the reach of children at a temperature of +10 to +30°C.

Opinion and reviews about the drug

So far, the effectiveness of the drug has not been proven directly through laboratory studies. There are various rumors about the advisability of its use. A number of studies have shown that it should be used only for preventive purposes, and for therapeutic purposes - with mild forms of diseases.

Reviews of doctors about liv.52

Chukhrov V.V.

psychotherapist
experience 24 years

02.10.18 19:41:44

	Rating 4.2 / 5
Efficiency
Price quality
Side effects

An old, time-tested Indian drug that helps to stop various manifestations of hepatic dysfunction (colic, a feeling of heaviness in the right hypochondrium, moderate signs of intoxication). I use it in the treatment of patients with addictions when liver function suffers.

The drug is not the cheapest. Allergic reactions are possible.

Kartoyatskaya K.V.

gastroenterologist
experience 11 years

23.06.17 09:51:29

	Rating 2.5 / 5
Efficiency
Price quality
Side effects

The drug has been used in Russia for a very long time. Against the background of taking the drug, she noted a significant positive trend. The drug is not cheap, but available to many. Another plus is that it can be used at a young age. Recently, a lot of articles have been written about side effects drug, and therefore ceased to use in practice.

Izyumov S.V.

psychiatrist
experience 21 years

09.06.16 22:33:14

	Rating 2.5 / 5
Efficiency
Price quality
Side effects

An old proven drug, again from herbs. The effect is weak, but a wide range of therapeutic action.

Caution should be used in allergy sufferers, be sure to collect an anamnesis. And their number is growing every year! In practice, about 20-30% of patients develop some kind of intolerance.

Some take it with pleasure, as herbs, although from India.

Aleksandrov P. A.

infectious disease specialist
experience 10 years

09.06.16 15:08:46

The liver is a natural filter of the body, which passes through itself all the toxic substances and toxins. She suffers from malnutrition, polluted air and bad habits, and is also exposed to viral and bacterial infections. The treatment regimen for any disease will include not only etiotropic drugs (those that eliminate its cause), but also symptomatic and supportive agents. Liver treatment Leaf 52 is a technique recommended by many experts. This is an Indian herbal medicine that helps to restore the liver in many of its pathologies.

Composition and form of release

Liv 52 is available in the form of tablets or drops. They have a similar composition, but differ in dosage calculation. They contain only natural plant components that have a complex effect on the condition of the liver and contribute to its recovery in many diseases. The fact is that after the processing of plant substances, a large number of biologically active components remain, which are used to create hepatoprotectors. These are various alkaloids, and steroid saponites, and glycosides, and vitamin C in high concentration. All of them affect the state of the liver and are useful for hepatitis and other pathologies.

Several plants are used to create Liv 52:

wild chicory - increases appetite, protects the liver tissue from the harmful effects of environmental factors, has a choleretic and diuretic effect;
prickly capers - the main component, the source of most useful biologically active substances, vitamins and minerals;
nightshade is a plant valued for its analgesic, antispasmodic, hepatoprotective and anti-inflammatory effects;
western cassia - participates in the processes of bile secretion and emulsification of fats in the small intestine, which significantly relieves the load on the liver;
terminalia arjuna - has a general strengthening and tonic effect;
Tamarix Kalsky is a well-known hepatoprotector, which is used to create many pharmaceutical drugs to support liver function;
yarrow - a remedy that is used for violations of the outflow of bile, as well as to relieve spasmodic pain in the liver and gallbladder.

The use of herbal preparations to protect and support the liver is no less effective than the use of chemical synthesized substances. Liv 52 has been on the pharmaceutical market for a long time and has proved its effectiveness against a number of liver pathologies. All the ingredients here are selected in the right proportions, so the drug is highly effective and has a low degree of side effects. In addition, the effect of plant substances will be more gentle for the body, especially during the period of treatment for hepatitis of any origin.

Liv 52 is also available in the form of drops, which are convenient to give to preschool children.

Mechanism of action and benefits for the liver

Liv 52 (from the word "liver" - liver) is a complex hepatoprotective agent. Unlike many other analogues, it is highly effective, and it can be taken only according to indications and as prescribed by the attending physician. It is also worth observing the indicated dosages.

When used correctly, the drug produces a number of positive effects:

anti-inflammatory;
antioxidant;
analgesic and antispasmodic;
general firming;
choleretic.

The removal of inflammation is the first condition for recovery in various pathologies of the liver. Inflammatory processes reduce the ability of the organ to perform its functions, gradually destroy healthy cells. Regeneration of the hepatic parenchyma is rapid, but only if there are normal functional hepatocytes that can divide. For this reason, the main goal of treatment for hepatitis of any etiology and other liver pathologies is to stop inflammation in time. If it progresses, the cells will begin to die off with the formation of dense connective tissue scars and the development of cirrhosis.

Liv 52 cleanses the liver by normalizing the outflow of bile. One of the functions of the liver is the secretion of bile and its removal through the ducts to the gallbladder, from where it will enter the small intestine. With inflammatory or degenerative changes in the organs of the hepatobiliary tract, the biliary tract is compressed, which causes cholestasis - bile stasis. The ability of the liver to secrete bile may also be reduced, which can be restored by taking Liv 52.

Some components of the drug have a pronounced analgesic and antispasmodic effect. Pain is one of the main signs of hepatitis or hepatosis, which is a direct indication for taking Liv 52. This medicine eliminates the need to take painkillers separately. They can be toxic to the liver, and long-term use is likely to lead to drug-induced hepatitis.

Indications for use

Liv 52 may be administered alone or in combination with other drugs for the treatment of liver diseases. The instructions for use indicate a list of indications for which this drug may be effective:

hepatitis (inflammation of the liver) of any origin - viral, medicinal, toxic, in acute or chronic form;
hepatosis - infiltration of the liver with fatty inclusions;
cirrhosis;
reducing the patient's weight to a critical point;
in order to prevent long-term use of antibiotics, anti-inflammatory, antiviral and other groups of drugs;
during the recovery period after chemotherapy and the use of other toxic drugs.

Liv 52 can be an independent treatment for the liver. However, it is more commonly used in combination with other medicines that will affect the causes of the disease. During periods of exacerbation of hepatitis, this medicine is used with caution.

The main advantage of Liv 52 over analogues is its completely natural composition.

Contraindications and possible side effects

Despite the natural plant composition and proven effectiveness, Liv 52 is not suitable for all patients. The list of contraindications to its use includes:

increased individual sensitivity to one or more components of the remedy;
the period of pregnancy and breastfeeding;
tablets are contraindicated in children under 6 years of age, drops - in babies under 2 years of age.

Usually the drug is well tolerated and does not cause side effects. In some cases, allergic reactions may develop. They are manifested by fever, nausea and vomiting, the appearance of a rash on the skin or swelling of the mucous membranes. If one of these symptoms appears, it is worth stopping the course of treatment with Liv 52 and replacing it with one of the analogues.

Instructions and dosages

The dosage of the drug depends on the form of its release, as well as on the age of the patient and his diagnosis. The course of treatment is also calculated individually, but in most cases it can continue until the symptoms of the disease disappear completely. The tool is not addictive and can be used for a long time.

Liv 52 tablets are taken in the following dosage:

children from 6 years old - 1 or 2 tablets 3-4 times a day half an hour before meals;
adults - 2-3 tablets 3-4 times a day half an hour before meals;
as a preventive measure for adults - 2 tablets twice a day.

The drug in the form of drops for oral administration (Liv 52 K) is prescribed individually:

children from 2 years - 10-20 drops 2 times a day;
adults - 1-2 tablespoons a day;
For prevention, one spoon per day is enough.

The course of treatment lasts until full recovery. However, in some diseases (with cirrhosis), the liver does not completely regenerate, so the drug continues to be taken for a long time. In this case, it allows you to maintain a state of health at a constant level and prevent the development of complications.

Liv 52 is a complex phytopreparation intended for the treatment and prevention of pathologies of the liver and gallbladder. For several decades, Liv 52 has been used for hepatitis of various origins and to protect the liver from drug and alcohol intoxication.

There are polar opinions about the effectiveness of the drug and its ability to have a negative, and even malignant effect on the liver. Like it or not, you can understand by examining in detail the mechanism of action of the drug and the reviews of patients treated with Liv 52.

Liv 52 is considered one of the “oldest” hepatoprotectors. It first went on sale worldwide from India in the 50s of the last century. Initially, it was used as a complex medicine for hepatitis and other liver diseases, then after tests in different countries it was also prescribed for diseases of the gallbladder, as it has a pronounced choleretic effect.

medicinal group

Hepatoprotectors are drugs designed to protect the liver from the effects of negative factors, normalize intercellular metabolism and restore the organ during various diseases. Currently, drugs with a hepatoprotective effect are created from phospholipids, amino acids, synthetic substances, as well as from various plants.

It is difficult to say which type of hepatoprotectors is more effective, since a certain medicine is selected for each disease. In addition, it is necessary to take into account the age and condition of the patient, his drug tolerance and what drugs are prescribed together with hepatoprotectors. Patient reviews are mixed - some are helped by phospholipid preparations, others by synthetic agents, and still others see the effect only from herbal remedies.

Regardless of the composition of the drug, it must be borne in mind that any hepatoprotector must have the following functions:

Remove toxins from liver cells.
Normalize protein, carbohydrate and fat metabolism.
Protect healthy liver cells and repair damaged ones.

The composition and properties of the drug

The effect of the drug on the body is determined by its composition - it contains the roots, seeds, bark and herbs of plants that have a positive effect not only on the liver, but on the whole organism as a whole.

Ingredients of the drug and their beneficial properties:

The tablet form also contains iron oxide. In addition, each form of the drug contains extracts and extracts from various flowers and herbs with hepatoprotective and choleretic properties, as well as auxiliary components.

Due to its composition, Liv 52 performs the following functions:

Improves biochemical indicators of hepatic functions.
Normalizes fat metabolism.
Restores liver cells and improves the outflow of bile by increasing the contraction of the gallbladder.
By increasing the content of tocopherol in hepatocytes, the drug increases their antioxidant properties.
Provides the synthesis of phospholipids and proteins necessary for the reproduction and restoration of liver cells.
When the liver is damaged by alcoholic beverages, the drug reduces the concentration of ethyl alcohol in the blood and urine, prevents the appearance of a hangover and accelerates the excretion of intermediate metabolic products from the body, leading to intoxication of the body.

Instructions for use

The medicine has practically no contraindications for taking, more precisely, there are only four of them:

Pregnancy at any time.
lactation period.
Hypersensitivity to any component of the drug.
Age restrictions: drops can be from 2 years old, and tablets from 6 years of age.

How to use:

In children from 6 years old, take 1-2 tablets or capsules 3 times a day for medicinal purposes and 2 times a day as a preventive measure.
Adults are prescribed 2-3 tablets or capsules 3 times a day.
From 2 years of age, 11 to 20 drops of the solution are prescribed 2 times a day.
Adolescents and adults can be prescribed from 20 to 160 drops 2 times a day.

Treatment of other gastrointestinal diseases

Liv 52 is used not only for liver pathologies, but also for diseases of other organs of the digestive system:

Possible consequences and development of cancer

Since Liv 52 consists of plant materials, it practically does not cause negative reactions in the body. Sometimes allergic manifestations appear, and in most cases they occur in patients with a tendency to allergies. Even less common are gastrointestinal disorders, manifested by abdominal pain or diarrhea. If adverse reactions occur, stop treatment and contact your doctor.

Recently, information has increasingly appeared that Liv 52 does not cure, but rather causes liver pathologies, moreover, of a malignant nature. This opinion among patients is supported by the fact that in the United States they have already abandoned treatment with this drug, but at the same time another drug with a similar composition is being produced there. Therefore, information about the dangers of Liv 52 can be considered as a marketing ploy of some pharmaceutical companies.

If we consider the properties of each plant that is part of the drug, we can see that none of them has a carcinogenic effect, that is, they do not cause cancer cells to multiply in the body.

But do not forget that at its core, Liv 52 is a stimulant drug. If malignant processes are just beginning to form in the liver, then taking the drug will provoke the rapid growth of the tumor, but in the absence of oncology, the patient has nothing to fear.

To avoid consequences in the form of liver cancer, it is necessary to undergo an examination before treatment and not try to self-medicate.

Experts recommend not taking Liv to 52 patients who have a hereditary tendency to cancer, have a history of cancer, and those who have severe cirrhosis of the liver, as it often turns into carcinoma.

Also, to exclude side effects, it is important to take into account the interaction of Liv 52 with other medicines: the drug reduces the absorption and effect of tetracyclines and drugs with ibuprofen. It is not recommended to use alcoholic drinks during treatment, since as a result of their administration, the effectiveness of the drug decreases, and the body receives an additional load.

In this article, you can read the instructions for using the drug Liv 52. Reviews of site visitors - consumers of this medicine, as well as opinions of doctors of specialists on the use of Liv 52 in their practice are presented. We kindly ask you to actively add your reviews about the drug: the medicine helped or did not help get rid of the disease, what complications and side effects were observed, perhaps not declared by the manufacturer in the annotation. Liv 52 analogues in the presence of existing structural analogues. Use for the treatment of hepatitis, cirrhosis and other liver diseases in adults, children, as well as during pregnancy and lactation. The composition of the drug.

Liv 52- combined herbal preparation. It has hepatoprotective, antitoxic, anti-inflammatory, choleretic, antioxidant, antianorexic effects. It helps to improve the process of digestion and assimilation of food.

The hepatoprotective effect of Liv 52 is due to the antioxidant and membrane-stabilizing properties of its constituent components. The drug increases the level of endogenous tocopherols in hepatocytes and the level of cytochrome P450. Liv 52 stimulates the biosynthesis of proteins and phospholipids. Promotes the restoration of hepatocytes, reduces degenerative, fatty and fibrotic changes, enhances intracellular metabolism.

The drug regulates the level of plasma proteins in the blood, normalizing the ratio of albumin / globulin. Provides normalization of the level of plasma transaminases, cholesterol, triglycerides, reducing the manifestations of dyslipidemia. Reduces bilirubin and alkaline phosphatase. Increases the ability of the liver to store glycogen.

Improves the colloidal properties of bile, prevents the formation of gallstones. Improves the contractile function of the gallbladder.

Stimulates hematopoiesis.

With alcoholic liver damage, the drug reduces the level of ethanol in the blood and urine; increases the activity of acetaldehyde dehydrogenase, which helps to reduce the level of acetaldehyde; prevents the binding of acetaldehyde to cell proteins, accelerates its excretion. By preventing the damaging effect of acetaldehyde on hepatocytes, the drug reduces the risk of developing a "hangover" syndrome.

Prickly caper root powder + Common chicory seed powder + Iron oxide (mandura basma) + Black nightshade powder + Arjuna terminalia bark powder + Western cassia seed powder + Common yarrow herb powder + Tamarix Gali powder + Steamed extracts from a mixture of medicinal raw materials: eclipta white, philanthus niruri, spreading berhavia, heart-leaved tinospora, sowing radish, officinalis officinalis, Ceylon pigweed, currant embelia, hebula terminalia (myrobalan tree), medicinal fumes + excipients (Liv 52 tablets).

Prickly caper root extract + Common chicory seed extract + Black nightshade extract + Arjuna terminalia bark extract + Western cassia seed extract + Common yarrow herb extract + Tamarix Gali extract + Water extract (1:10) processed over steam from a mixture of medicinal raw materials (taken in equal amounts of 0.64 mg): white eclipts, philanthus niruri, Berhavia sprawling roots, stems of tinospora cordifolia, seeds of common radish, fruits of officinalis officinalis, roots of Ceylon pigweed, fruits of currant embelia, peel of fruits of terminalia chebula, fumes officinalis + excipients (drops of Liv 52 K).

The therapeutic effect of Liv 52 is due to the combined action of its components, so kinetic observations are not possible.

acute and chronic infectious, toxic and medicinal hepatitis; cirrhosis of the liver in adults; fatty hepatosis; anorexia; prevention of toxic liver damage (caused by antibiotics, anti-tuberculosis drugs, antipyretics).

Release form

Drops for oral administration Liv 52 K (sometimes erroneously called syrup).

Instructions for use and regimen

For prophylactic purposes, the drug is prescribed 2 tablets 2 times a day.

For therapeutic purposes, children over 6 years of age are prescribed 1-2 tablets 2-3 times a day, adults - 2-3 tablets 2-3 times a day.

The drug in the form of drops is prescribed for therapeutic and prophylactic purposes for children over 2 years old, 10-20 drops 2 times a day, adults - 80-160 drops (1-2 teaspoons) 2 times a day.

Side effect

allergic reactions; dyspepsia. hypersensitivity to the components of the drug; pregnancy; lactation.

Use during pregnancy and lactation

The drug is contraindicated for use during pregnancy and lactation.

Use in children

For therapeutic purposes, children over 6 years of age are prescribed 1-2 tablets 2-3 times a day.

The drug in the form of drops is prescribed for therapeutic and prophylactic purposes for children over 2 years old, 10-20 drops 2 times a day.

special instructions

With caution, the drug should be prescribed to patients with acute diseases of the stomach and intestines.

Liv 52 K ( dosage form- drops) does not contain ethyl alcohol (alcohol) and can be used in children with diseases of the liver and biliary tract.

drug interaction

The drug interaction of the drug Liv 52 is not described.

Analogues of the drug Liv 52

Liv 52 has no structural analogues for the active substance.

Analogues by pharmacological group (hepatoprotectors):

D, L-Methionine; L-Methionine; S-adenosylmethionine; Alpha lipoic acid; Antraliv; Berlition; Betaine Citrate UPSA; Brenziale forte; Vitanorm; Hepa Merz; Hepatosan; Hepatofalk planta; Heptor; Heptral; Geptrong; Glutargin; Glutargin alkoklin; Cavehol; Karsil; Karsil Forte; Criomelt MN; L-ornithine-L-aspartate; Legalon 140; Legalon 70; Livodex; Livolife Forte; Lipoic acid; Lipoid PPL 400; Lipoid C 100; Maksar; Methionine; Metrop GP; Milife; Molixan; Octolipen; Ornitsetil; Rezalut Pro; Silegon; Silibinin; Silimar; Silymarin; Silymarina Sediko; Sirepar; Thiolipon; Thiotriazoline; Tykveol; Urdox; Urso 100; Ursodez; Ursodeoxycholic acid; Ursodex; Ursoliv; Ursor; Ursosan; Ursofalk; Phosfonciale; Hepabos; Choludexan; Betaine Citrate Bofur; Exhol; Erbisol; Espa Lipon; Essentiale N; Essentiale forte N; Essential phospholipids; Essliver.

In the absence of analogues of the drug for the active substance, you can follow the links below to the diseases from which the corresponding drug helps and see the available analogues for the therapeutic effect.

Liv-52 is a multicomponent drug with a hepatoprotective effect, which is determined by the individual properties of each herbal ingredient that is part of it. What components are included in this complex preparation?

Tablet form:

Chicory (dry extract); caper bark; Nightshade; Terminalia arjuna; Cassia western; Tamarix Gallic; Yarrow seed; iron oxide. Chicory seed extract; caper bark; Nightshade; Terminalia arjuna; Cassia western; Tamarix Gallic; Yarrow seed.

What helps Liv-52? As a hepatoprotector, the drug protects hepatocytes from damage and promotes their active regeneration. In addition, Liv-52 increases the activity of the biosynthetic function of liver cells, inhibits the oxidation of lipid components, protecting cell membranes from the negative effects of oxidation products on them. The action of the drug is also aimed at binding toxins and other harmful substances that have entered the body and adversely affect the function of hepatocytes. The drug Liv-52 successfully fights congestion in the biliary tract, eliminating the effects of dyskinesia and normalizing the digestive process, increasing the patient's appetite. To the above properties of the drug, you can also add a choleretic, antioxidant and mild diuretic effect.

The main indications for the use of Liv-52:

Diffuse liver damage (prevention and treatment); Toxic lesions of hepatocytes; Fatty degeneration of the liver; Hepatitis of various origins; Prevention of liver damage for the period of taking chemically aggressive drugs, for example, antitumor, antibiotics, etc.; Prevention of liver damage during radiological treatment (irradiation); Dyskinesia of bile ducts; Cholecystitis, cholecystocholangitis; Paraproteinemia (presence of functionally defective proteins in the blood); Anorexia, weight loss in children.

Contraindications to taking the drug

A contraindication to treatment with Liv-52 is hypersensitivity to any ingredient of the drug, pregnancy and breastfeeding. The drug is not recommended for children under five years of age.

If during treatment with Liv-52 any allergic manifestations are noted - rashes, itching, skin hyperemia or diarrhea occurs, then you should immediately stop using the drug and consult a doctor about the possibility of further continuation of the course.

How to take Liv-52 correctly

Tablets: Adult patients are recommended to take two to three tablets 3-4 times a day. For children from six years old, the dosage is one to two tablets, also 3-4 times a day. As everybody homeopathic remedies Liv-52 is taken either half an hour before meals, or an hour after it. For the purpose of prevention, it is enough to take the drug twice a day, two tablets.

Liquid: for adults, take 80 to 160 drops of the drug (1-2 teaspoons) twice a day. Prophylactic dose - 80 drops per day at a time. Children from six years old - 10-20 drops twice a day.

Interaction with other medicines

The combination of Liv-52 with ibuprofen reduces the therapeutic effect of the latter; The use of the drug together with antibiotics of the tetracycline group reduces their effectiveness; During the course of treatment is not recommended to drink alcohol.

Cost and analogues

The price of Liv-52 fluctuates between 280-350 rubles. You can get exact information about how much the drug costs just before buying it at the pharmacy network in your locality.

In any case, due to various factors, the patient has the opportunity to choose for himself a suitable analogue of Liv-52:

Hepatophyte; Gepabene; Karsil; Essentiale; Rezalut pro; Antral; Enerliv; Heptral and others.

Expert reviews

It should be noted that reviews of Liv-52 are quite contradictory. A number of specialists highly appreciate the therapeutic properties of this drug, while other hepatologists are skeptical about it. In the medical literature, there is information that the properties of Liv-52 declared by the manufacturer do not correspond to reality. If clinical trials of the use of a drug for the treatment of a viral form of hepatitis demonstrated a decrease in the level of bilirubin and a slight loss of body weight in patients, then during the treatment of alcoholic hepatitis, the effect of using Liv-52 was almost equal to placebo. In addition, the intoxication indicator of the drug was also not noted.

Experts also refer to some cases of using Liv-52 in acute pathological conditions of the liver, when a significant deterioration in the patient's condition occurred. The use of the drug in liver failure did not affect the mortality rate of patients, and in some cases even worsened it.

Taking into account all of the above, it is advisable to consult with your doctor before using Liv-52 and strictly follow his recommendations.

The price is from 280 to 350 rubles.

Compound

One tablet of Liv 52 contains: 65 mg root powder prickly capers, 65 mg seed powder common chicory, 33 mg iron oxide, 32 mg powder black nightshade, 32 mg bark powder arjuna terminalia, 16 mg seed powder western cassia, 16 mg herb powder common yarrow, 16 mg powder gal tamarix.

These ingredients are treated with steam of an extract from a mixture of the following medicinal raw materials: philanthus niruri, common radish, spreading berhavia, cordifolia tinospore, Ceylon pigweed, white eclipta, officinalis emblica, chebul terminalia, currant embelia, officinalis fumes.

Additional substances: microcrystalline cellulose, magnesium stearate, sodium carboxymethylcellulose, croscarmellose sodium.

One milliliter of Liv 52 K contains: 17 mg of prickly caper extract, 17 mg of seed extract common chicory, 8 mg extract black nightshade, 8 mg bark extract arjuna terminalia, 4 mg seed extract western cassia, 4 mg herb extract common yarrow, 4 mg extract gal tamarix.

These ingredients are steamed with an extract from a mixture of the following medicinal raw materials: philanthus niruri, common radish, cordifolia tinospora, spreading bergavia, Ceylon pigtail, white eclipta, officinalis emblica, chebula terminalia, currant embelia, officinalis fumes.

Additional substances: sodium propylparaben, sodium citrate, sucrose, sodium methylparaben, water, peach flavor.

Release form

Green-gray biconvex tablets of a round shape with splashes. 100 tablets in a plastic bottle - one bottle in a cardboard box. Dark brown drops for oral use. 60 ml in a dark glass bottle - one bottle with a pipette dispenser in a cardboard box.

pharmachologic effect

Hepatoprotective, choleretic action.

Pharmacodynamics and pharmacokinetics

Combined phytopreparation. It has antitoxic, hepatoprotective, choleretic, anti-inflammatory, anti-anorexic, antioxidant effects. Promotes the assimilation of food and stimulates the process of digestion. The hepatoprotective effect is due to the membrane-stabilizing and antioxidant properties of the drug components. The drug increases the content endogenous tocopherols in liver cells and concentration cytochrome P450. Stimulates the production of phospholipids and proteins. Helps restore hepatocytes, inhibits fatty, degenerative and fibrotic changes, activates intracellular metabolism.

The drug normalizes the level of plasma proteins blood, adjusting the ratio globulins And albumin. Provides normalization of concentration triglycerides, cholesterol, plasma transaminases suppressing manifestations dyslipidemia. Lowers the level alkaline phosphatase And bilirubin. Increases the ability of the liver to store glycogen.

With alcohol damage to liver tissues, the drug lowers the level ethyl alcohol in urine and blood; enhances activity acetaldehyde dehydrogenase, which accelerates the decrease in concentration acetaldehyde; stops responding acetaldehyde with cell proteins, accelerates its evacuation from the body. Preventing damaging effects acetaldehyde on liver cells, the drug reduces the risk of a "hangover" syndrome.

Improves colloidal indicators of bile, prevents the production of gallstones. Stimulates the peristalsis of the gallbladder, as well as hematopoiesis.

Indications for use

The following are the indications for the use of Liv 52:

toxic, infectious and medicinal hepatitis acute and chronic; fatty hepatosis; cirrhosis of the liver in adults; anorexia; prevention of toxic changes in the liver (caused anti-tuberculosis drugs, antibiotics, antipyretics).

Contraindications

Pregnancy or lactation. Hypersensitivity to the ingredients of the drug.

Side effects

Skin reactions: edema skin, rash, hyperemia, itching skin reactions including epidermal toxic necrolysis. Digestive reactions: nausea, dyspeptic phenomena, loosening of the stool. When using the drug, it is possible to develop hypersensitivity reactions.

Instructions for use Liv 52 (Method and dosage)

The drug should be taken orally, regardless of the meal.

Tablets Liv 52, instructions for use

For preventive purposes, the drug is taken 2 tablets twice a day. For therapeutic purposes, children from 6 years old take 1-2 tablets three times a day, and adult patients - 2-3 tablets up to three times a day.

How to take the drug in the form of drops?

Overdose

There are no data on cases of overdose by means.

Interaction

Features of pharmacological interaction with other drugs have not been studied.

Terms of sale

Over the counter.

Storage conditions

Keep away from children. Store in a dry place at room temperature.

Best before date

special instructions

It is recommended to prescribe the drug with caution to patients with acute diseases of the digestive system.
Liv 52 does not contain ethyl alcohol and is approved for use in children with lesions of the biliary tract and liver.

Liv 52 in bodybuilding

The drug is often used in bodybuilding, as hepatoprotector with long courses of drug and hormonal stimulation of muscle growth and athletic capabilities.

Analogues

Coincidence in the ATX code of the 4th level:

The most accessible analogues: Karsil, Bonjigar, VG-5, Hepa-Merz, Hepatoxan, Geptrong, Criomelt MN, Laennec, Metrop GP, Gemaxol, Thiotriazolin, Phosphogliv, Hofitol, Silibinin, Silimar, Legalon, Essentiale.

Which is better: Karsil or Liv 52?

Karsil, like Liv 52, is a herbal preparation with similar pharmacodynamic parameters and indications for use. Patients' opinions about which drug is better differ, and there are no credible studies of the comparative effectiveness of these drugs. The choice must be made based on the recommendations of the doctor and individual sensitivity.

children

For therapeutic purposes, children from 6 years of age take Liv 52 1-2 tablets three times a day.

For therapeutic or prophylactic purposes, children from 2 years of age take Liv 52 K, 11-20 drops twice a day.

During pregnancy and lactation

The drug is contraindicated for use during these periods.