The use of syrup and drops of sinecode for the treatment of cough in children. Sinekod syrup - instructions for use Sinekod tablets instructions for use for adults

Sinekod (syrup, drops, dragees) - instructions for use, analogues, reviews, price

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The site provides reference information for informational purposes only. Diagnosis and treatment of diseases should be carried out under the supervision of a specialist. All drugs have contraindications. Expert advice is required!

bluecode is a non-narcotic antitussive drug central action, designed to relieve painful dry cough. This drug suppresses the cough reflex at the level of the central nervous system, effectively stopping the painful and debilitating symptom. Sinekod is a non-narcotic drug, so it can be used to stop a dry cough for a fairly long period of time.

Composition, release forms and names

Currently, Sinekod is available in the following dosage forms:

Dragee for oral administration;
Syrup for oral administration;
Drops for oral administration for children and adults.

The listed dosage forms of Sinekod are at the same time varieties of the drug. Drops for children and adults are often simply called "Children's Sinekod", since it is this dosage form that can be used to stop coughing in babies almost from birth, and contains a corresponding indication in the name. The syrup can also be used for children, but only from the age of three. Therefore, the term "children's Sinekod" can mean both syrup and drops at the same time. Such inaccuracy in everyday definitions can create confusion, therefore, when using the term "Children's Sinekod", it is necessary to clarify which form, which is allowed for use by children, is meant in this particular case.

Dragees are often mistakenly called tablets because of their resemblance. Dragees are outwardly identical to tablets, and the differences between them are only in the technological features of preparing the mass from the main and auxiliary substances. But the technological intricacies of the production process are only important to pharmacists, not to consumers, so it is perfectly acceptable for people using the medicine to call dragees pills. However, Sinekod is not available in tablets, therefore, when someone says "tablets", he means exactly the dosage form of the dragee.

The composition of all dosage forms of Sinekod includes the same active substance - butamirate. However, the amount of butamirate in different forms of the drug is different - for example, each dragee contains 20 mg of the active substance, syrup - 1.5 mg per 1 ml, and drops for adults and children - 5 mg per 1 ml.

Tablets contain lactose, talc, colloidal titanium dioxide and macrogol as excipients. Syrup and drops contain the same following excipients:

Glycerol;
sodium saccharinate;
Benzoic acid;
Vanillin;
Ethanol;
Sodium hydroxide;
Distilled water.

Syrup and drops differ from each other only in the concentration of the active substance, the amount of solvent and the name of the dosage form.

Sinekod dragees have a round shape with flat sides and are colored red. Available in packs of 10 pieces. Drops are a clear, colorless or slightly yellowish solution with a characteristic vanilla odor. Available in dark glass bottles of 10 ml and 20 ml. The syrup is a clear liquid with a characteristic vanilla odor, available in dark glass bottles of 100 ml and 200 ml.

Therapeutic action of Sinekod

Sinekod has an antitussive therapeutic effect, which is provided by the active ingredient of the drug. This effect consists in stopping cough by suppressing the activity of the cough center of the brain. That is, Sinekod suppresses the work of the cough center in the brain, as a result of which the bronchi do not receive the necessary signal, and the person stops coughing.

Due to the fact that cough relief is achieved by suppressing a specific physiological center in the brain, Sinekod belongs to centrally acting antitussive drugs. This means that the drug completely turns off the cough reflex at the level of the brain. Therefore, no irritants can cause a cough again as long as the action of Sinekod continues.

In addition to cough suppression, Sinekod has the following therapeutic effects:

Bronchodilatory action (expands the lumen of the bronchi);
Decreased airway resistance;
Improving blood oxygenation (oxygen saturation).

Expanding the lumen of the bronchi and reducing the resistance of the airways provides a pronounced relief of breathing, as well as the penetration of more air into the lungs. Due to the increase in the volume of inhaled air, the blood is better saturated with oxygen and, accordingly, tissues and organs cease to experience oxygen starvation.

Thus, the therapeutic effects of Sinekod not only provide relief from dry cough, but also facilitate breathing and improve the supply of oxygen to the organs and tissues of the human body, which contributes to a faster recovery.

When taken orally, Sinekod is almost completely absorbed from the intestine into the bloodstream, and the maximum concentration of the active substance in the blood is reached after 1.5 hours. With subsequent doses, the concentration of the drug in the blood is maintained at the same constant level, and without increases. Sinekod does not accumulate in the blood, so the likelihood of an overdose, even with frequent use, is very low. The drug is excreted from the body by the kidneys at a very low rate. Thus, the half-life (the time during which half of the administered dose of the drug is removed from the body) of Sinekod is 6 hours.

Blue code and dry cough

Sinekod is intended specifically for the complete suppression of a dry, debilitating and painful cough that does not lead to sputum production. With this type of cough, the bronchial mucosa is swollen, inflamed and irritated. Moreover, irritation is due precisely to the inflammatory process and edema. And it is this feeling of irritation that is transmitted to the brain. The brain, in turn, processes this information and perceives irritation as a sign of the presence of some irritating substance directly on the bronchial mucosa, for example, sputum, dust, etc. Because of this perception, the brain instructs the cough center to provoke a cough, which is necessary to remove the irritating object. Usually, if there is any irritating substance on the bronchial mucosa, then as a result of coughing it is removed (for example, sputum or dust), the brain receives the appropriate information and stops giving commands to perform the cough reflex.

In the case of dry cough, there is simply no real substance that causes respiratory irritation that can be removed. In such a situation, the brain constantly gives a signal to start coughing, trying to remove the irritant. But since the irritant is absent, and the cause lies directly in the inflamed state of the mucous membrane, it will not be possible to eliminate it with a cough. However, the brain, not receiving a signal to stop the irritating effect on the bronchi, continues to send a signal to the cough center, making more and more attempts to remove the irritating substance. Naturally, such a cough does not bring benefit and relief, so it must be suppressed.

Sinekod is an effective remedy for suppressing just such a dry cough, since it blocks the work of the cough center of the brain. Despite the central mechanism of action, Sinekod is not a narcotic substance, so it is not addictive. Due to the lack of addiction and the numerous side effects inherent in narcotic antitussive drugs of central action, Sinekod can be used to suppress a dry, painful cough for a sufficiently long period of time. This is precisely the main advantage of Sinekod over narcotic antitussive drugs of central action (for example, Codelac, Codelmixt, Codterpin and others).

Sinekod as an antitussive is recommended for any dry cough that occurs against the background of various diseases, such as bronchospasm, pharyngitis, tracheitis, tracheobronchitis, bronchial asthma, chronic bronchitis, smoker's cough, pleurisy, performing diagnostic manipulations or operations, etc. In addition, Sinekod can be taken at the initial stages of a cold, when an excruciating dry cough appears without sputum production. However, it should be remembered that as soon as sputum appears in the respiratory tract, the use of antitussives, including Sinekod, should be stopped, since it must be removed from the bronchi.

Sinekod - indications for use

All dosage forms of Sinekod are indicated for use in the suppression of debilitating dry cough in various conditions and diseases, such as:

Smokers cough;
Dry cough accompanying respiratory diseases (tracheitis, laryngitis, pharyngitis, tracheobronchitis, bronchitis, bronchopneumonia, pleurisy, emphysema, bronchial asthma, etc.);
Cough suppression during diagnostic procedures (bronchoscopy, lavages, etc.);
Suppression of cough during surgical operations.

Any dosage form of Sinekod can be used if a person has the above indications. The choice of form is determined by personal ease of use, the required dosage and the possibility of use at a certain age. For example, children should be given only drops or syrup, while adults can choose any form of the drug at their own discretion.

Instructions for use

Consider the rules for the use of various dosage forms of Sinekod, as well as their dosage and duration of treatment for children and adults in the relevant sections.

Sinekod - instructions for use of syrup and drops

Drops and syrup must be taken before meals. Before use, it is recommended to shake the bottle with drops or syrup slightly to mix its contents well.

When using the syrup, take out the enclosed graduated cap and pour the required amount of the solution into it. All syrup poured into a measuring cap must be drunk. If more syrup is accidentally poured into the cap than necessary, then in no case should you try to pour it back into the bottle. In this case, you should simply pour the excess amount of syrup into the sink or toilet so as not to take too much of the drug. After measuring the required amount of syrup, it is drunk directly from the cap, without pouring into any other containers. After taking the syrup from the measuring cap, you can drink it with water. The cap after each use should be thoroughly washed with soap and dried with a towel or paper.

When using drops, prepare a clean spoon or a small container, such as a shot glass. The bottle is shaken several times, after which it is opened, turned vertically upside down and the required number of drops is measured into a spoon or small container. When the required number of drops is measured, you need to drink them directly from a spoon or a small container, and then drink a little water.

If syrup or drops are given to a child, then it is necessary to ensure that he drinks the entire measured amount. If the child spat out part of the measured syrup or drops, then you should not add a little Sinekod "by eye", it is better to give him the full dosage again after 2 hours.

For the relief of cough in children under 3 years of age, only Sinekod drops should be used. In children over 3 years old, drops and syrup can be used. And children over 6 years old can take Sinekod in any dosage form - drops, syrup or dragees (tablets).

In children and adults of any age, Sinekod can be used for cough relief for a maximum of 7 days without consulting a doctor. If after a week the cough has not gone away and is still bothering the person, then you should stop taking Sinekod and consult a doctor.

Since Sinekod suppresses cough, it cannot be used simultaneously with expectorant and mucolytic drugs, the action of which is aimed at facilitating and accelerating the removal of sputum from the respiratory tract. In fact, expectorants and antitussives have a diametrically opposite effect, so they cannot be used together. And mucolytic drugs thin the sputum and increase its volume, which, in combination with taking the antitussive Sinekod, can provoke the accumulation of secretions in the airways with the risk of bronchospasm and secondary infection of the lungs or small bronchi. In general, Sinekod is not recommended for use in combination with any other cough medicines, as this can lead to serious complications.

When using drops and syrup, it should be borne in mind that they contain sorbitol and saccharin, which are well tolerated in diabetes, so people suffering from this disease can take Sinekod preparations.

Sinekod tablets - instructions for use

Dragee Sinekod, which in everyday speech are usually called tablets, must be taken before meals. The required amount of dragee should be swallowed whole, not chewed, broken or crushed in other ways, but washed down with a small amount of clean water.

Dragee can be given to children over the age of six and adults. It is not recommended to give Sinekod in the form of a dragee to children under 6 years of age due to the high risk of suppression.

The cough medicine should not be taken for more than seven days. If, after a week of therapy with Sinekod, the cough does not go away, then you should immediately stop taking the drug and consult a doctor.

Also, Sinekod dragees cannot be used in combination with expectorant and mucolytic drugs, which are aimed at enhancing the excretion of sputum from the respiratory tract. The combined use of these drugs can provoke severe complications, including secondary infection of the respiratory organs with the development of pneumonia.

Dosages of Sinekod for children and adults

Dosages and frequency of use of drops, syrup and dragees of Sinekod are determined by the age of the child and do not depend on the severity or type of disease that provoked the appearance of a persistent, dry, debilitating and painful cough.

Drops Sinekod for the relief of cough in children of different ages and adults, it is recommended to take the following dosages:

Children aged 2 months to 1 year - take 10 drops 4 times a day;
Children aged 1 to 3 years - take 15 drops 4 times a day;
Children over 3 years old, adolescents and adults - take 25 drops 4 times a day.

It is recommended to take Sinekod drops every 6 hours. If such a regimen cannot be observed due to a longer night's sleep, then drops should be taken immediately before falling asleep and immediately after waking up. And the remaining dosages of drops should be taken at regular intervals throughout the day.

Adults and adolescents over 12 years of age can increase the dosage to 50 - 60 drops per dose. In children, the dosage of drops to exceed the recommended limits is not recommended. If the drug does not stop the cough, then you should not increase the dosage, but stop taking Sinekod and consult a doctor. Drops for oral administration is an antitussive drug used mainly in young children (under 3 years of age). Children over 3 years of age are recommended to give Sinekod in the form of a syrup, as it is better tolerated and tastes better, which is very important for a positive perception of the medicine by the child.

Children aged 3 - 6 years - take 5 ml three times a day;
Children aged 6 - 12 years - take 10 ml three times a day;
Children aged 12 - 15 years - take 15 ml three times a day;
Adolescents over 15 years of age and adults - take 15 ml four times a day.

The syrup is recommended to be taken at regular intervals of 8 hours. Sinekod syrup is excellent for use in children and adults, therefore, after reaching the age of three, it is recommended to take the drug in this form, and not in drops. Children over 6 years old can be given not only syrup, but also dragees, provided that they know how to swallow tablets.

Children aged 6 - 12 years - take 1 tablet twice a day;
Children 12 - 15 years old - take 1 tablet three times a day;
Adolescents over 15 years of age and adults - take 2 tablets 2 to 3 times a day.

Sinekod tablets must be taken at regular intervals. If the drug must be taken twice a day, then the interval between doses of 12 hours should be observed. When taken three times a day, the interval between them should be 8 hours.

Influence on the ability to control mechanisms

Any form of Sinekod (drops, syrup and dragees) can make a person drowsy, which reduces the ability to control mechanisms. Therefore, against the background of the use of Sinekod, any activities that require a high speed of reactions and concentration of attention should be abandoned.

Overdose

An overdose of Sinekod is possible, as a rule, with a single dose of a large amount of the drug. An overdose is manifested by the development of the following symptoms:

Drowsiness;
Dizziness;
Loss of sense of balance;
Lowering blood pressure.

Overdose treatment consists in accelerating the removal of Sinekod from the body, for which gastric lavage is performed, sorbents are given to a person (for example, activated charcoal, Polysorb, Polyphepan, etc.) and saline laxatives. In the future, symptomatic therapy is carried out, aimed at maintaining the normal functioning of the cardiovascular and respiratory systems.

Interaction with other drugs

At present, interactions of Sinekod with any other medicinal products have not been identified and described. Therefore, while taking Sinekod, you can continue to use any medicines that a person needs for other indications.

Synekod for children

Sinekod is approved for use in children from an early age (from two months), since it is a drug with a minimum number of side effects, with a low risk of severe complications and, according to the mechanism of action, does not belong to narcotic antitussives. All these properties allow the use of Sinekod for the effective relief of dry cough in children.

However, despite the safety of Sinekod compared to other antitussives, it is very relative. For example, Sinekod is capable of provoking laryngeal edema in children as a side effect, which can cause difficulty breathing or asphyxia. Such a side effect develops extremely rarely and with a much lower frequency than when using other antitussive drugs. But it exists and is theoretically possible, although it develops less frequently than with other drugs, and therefore Sinekod cannot be considered a completely safe medicine. Sinekod is only safer than other drugs, but, like almost all drugs, it is not a harmless remedy that can be used at your own discretion without consulting and prescribing a doctor.

That is why, despite the fact that Sinekod can be used to relieve cough in children, the drug should not be used without consulting a doctor. Also, the recommended dosages of Sinekod for children should not be exceeded, since the ability of their kidneys to excrete excess drug is limited, as a result of which an overdose can develop even with a minimal increase in the correct dose.

Sinekod during pregnancy and breastfeeding

Clinical trials of Sinekod on pregnant women, for obvious ethical reasons, were not carried out, therefore, from the point of view of evidence-based medicine, the drug cannot be considered completely safe for women who are carrying a child. However, animal experiments did not reveal any negative effects of Sinekod on the fetus and the course of pregnancy, so the drug can be considered conditionally safe.

In view of this conditional safety, Sinekod should not be taken during the first trimester of pregnancy, that is, until the 13th week of gestation, since it is during this period that the unlikely, but theoretically possible adverse effect of the drug on the fetus may be most pronounced. In the second and third trimesters of pregnancy (from the 13th week until delivery), Sinekod can be used provided that the benefit outweighs the hypothetical risk.

Dizziness usually resolves after the dosage of Sinekod is reduced.

Contraindications for use

All dosage forms of Sinekod are contraindicated for use if a person has the following diseases or conditions:

Individual hypersensitivity to the components of the drugs;
I trimester of pregnancy (from 1 to 13 weeks of gestation inclusive);
breastfeeding period;
Age under 2 months (for drops);
Age under 3 years (for syrup);
Age under 6 years (for dragees).

With caution and under medical supervision, it is necessary to use Sinekod in the second and third trimesters of pregnancy (from 13 weeks to delivery).

Sinekod - analogues

Sinekod has synonyms and analogues on the domestic pharmaceutical market. Synonyms are preparations that contain the same active substance as Sinekod. Analogues are preparations that contain another active substance, but have the same central antitussive effect as Sinekod.

Synonyms of Synecode

Omnitus syrup and tablets;
Panatus syrup and tablets;
Panatus Forte syrup and tablets;
Codelac Neo tablets, drops and syrup.

Analogues of Sinekod are the following drugs:

bithiodine tablets;
Bronchitusen Vramed syrup;
Broncholine sage syrup;
Broncholitin syrup;
Bronchoton syrup;
Bronchocin syrup;
Glaucine tablets;
Libeksin tablets;
Rengalin tablets and solution;
Estocin tablets.

Cheap analogue of Sinekod

The cheapest synonym for Sinekod is Codelac Neo, the cost of which ranges from 125 to 156 rubles.

Among the analogues of Sinekod, the following drugs are the cheapest:

Bronchitusen Vramed syrup - 51 - 64 rubles;
Broncholine sage syrup - 67 - 92 rubles;
Bronholitin - 58 - 73 rubles;
Bronchoton - 32 - 46 rubles.

Dry cough is a debilitating and painful symptom resulting from inflammation of the bronchial mucosa. He does not bring proper relief and benefit, in vain tearing his throat. Sinekod will help get rid of a cough - instructions for use, properties and indications will tell more about this drug.

Sinekod - an effective cough syrup

Release form and composition

The international name of the product is Sinecod. The international non-proprietary name is butamirate. Manufacturer: Swiss company Novartis Consumer Health.

Sinekod has 3 forms of release: dragees, syrup and drops for oral administration.

Dragee round and flat, orange hue. The pack contains 1 blister containing 10 dragees and official instructions. The syrup is translucent, sweet, with a strong vanilla flavor. In a cardboard box - 1 bottle of dark glass with a volume of 100 or 200 ml with a measuring cap, as well as an annotation. Drops are translucent, golden, smell of vanilla. The package contains 1 bottle of dark glass with a volume of 20 ml, a dispenser in the form of a dropper and instructions.

Price and analogues of Sinekod

Sinekod is a medium price category tool.

You can buy it at the following rates:

Dragee: 210-260 rubles.
Syrup: 250-410 rubles.
Drops: 320-425 rubles.

In pharmacies, you can find Sinekod analogues that have either a similar composition or an identical therapeutic effect.

List of the most popular drugs that can replace Sinekod.

Name	Short description	Price
	A drug with a similar active ingredient contains a lower dose of butamirate. Tablets or syrup.	180-230 rubles
Codelac Neo	Generic with the same form of release and dose of the active substance. It costs less, but is more often accompanied by side effects.	150-275 rubles
Panatus Forte	A product with butamirate in the base, produced exclusively in the form of a syrup. It is completely similar to Sinekod syrup, but has a lower price.	190-250 rubles
bronchoton	A combined preparation in the form of a syrup that relieves the cough reflex and inflammation. Has many side effects.	60-85 rubles
	A complex remedy that has a therapeutic and cough-suppressing effect. Tablets or drops.	150-350 rubles
	Herbal syrup that dilates the bronchi and reduces swelling. Contains an alkaloid in the composition, it is considered toxic.	80-110 rubles
	A syrup used for both dry and wet coughs. It has a pronounced mucolytic effect.	295-400 rubles
	Belarusian syrup or drops for oral administration with a similar effect and low cost.	115-210 rubles
Influenza-broncho	Drops or syrup that dilute sputum, relieve inflammation and turn off the cough reflex.	110-145 rubles
Bronchitusen Vramed	Combined cough syrup, which has many contraindications and adverse reactions. Quickly eliminates the symptom, but does not treat the cause.	110-135 rubles
	A complex remedy in the form of tablets or syrup that treats respiratory diseases.	250-415 rubles
Fluditec	Mucolytic drug that regenerates the mucosa and relieves the cause of coughing. Sold in the form of adult and children's syrup.	350-380 rubles

Indications for use

Sinekod is used to suppress cough in such conditions:

Unproductive cough in various diseases.
A symptom called "smoker's cough".
Reflex in diagnostics and surgical interventions.

Sinekod helps to get rid of cough

The main effect of the drug is the elimination of the symptom. It has a weak therapeutic effect due to the saturation of organs and tissues with oxygen, but this is an auxiliary effect.

pharmachologic effect

Sinekod is a non-narcotic antitussive agent of central action. It acts on the GM cough center and suppresses the symptom. The cause of the cough and the irritants that provoke it do not disappear, but the reflex is turned off for a while.

In addition to fighting cough, Sinekod does the following:

Expands the bronchi, allowing more air to enter the body.
Reduces lung resistance, making breathing easier.
Increases the saturation of organs and tissues with oxygen.

Sinekod is used only for dry, so-called "unproductive" cough. If the medicine will slow down the cough when expectorating the secret, it will begin to accumulate, which can cause bronchospasm or infection.

Instructions for use Sinekod

The drug must be taken orally:

the dragee is swallowed and washed down with water;
syrup is poured into a cap and drunk;
drops are diluted in water and drunk.

Drops are drunk 4 times a day, syrup - 3 times, dragees - 2-3 times.

For adults

The remedy should be drunk every 6-8 hours:

25 drops for oral administration;
15 ml of syrup;
2 tablets 2-3 times a day.

Taking the drug is acceptable for 1-2 weeks.

You need to use syrup every 6-8 hours

For children

The scheme of taking the medicine depends on the age of the child and the form of the remedy.

Children over 15 years of age drink the drug according to the scheme for adults.

During pregnancy and lactation

The tool is forbidden to use when breastfeeding, as well as during pregnancy in the 1st trimester. At a later date, it is permissible to use the drug with strict indications and under the supervision of the attending physician.

Possible side effects

Rare negative effects that accompany the use of Synekod include:

sleepy state;
dizziness;
nausea and vomiting;
diarrhea, flatulence;
itching, rashes, redness of the skin.

Diarrhea may occur after taking Sinekod

These side effects are rare. Most often, the use of Sinekod is not accompanied by unpleasant symptoms.

Contraindications

The bans on receiving Synecode look like this:

Use the drug in the 2nd and 3rd trimesters of pregnancy with caution.

Synecode Compatibility

With other medicines

Due to the cough-suppressing effect of the drug, it cannot be combined with mucolytics, so as not to provoke the occurrence of bronchospasm and infection. Compatibility with other groups of drugs has not been studied.

With alcohol

Drinking alcohol during treatment is not recommended.

What is better and how are they different?

Sinekod or Omnitus

These drugs have the same active ingredient, but Omnitus has a more pronounced therapeutic effect. It helps the outflow of sputum, relieves inflammation and swelling. Omnitus has fewer side effects and also costs almost half the price.

The only disadvantage of the drug is the impossibility of its use in children under 3 years of age.

Omnitus cough syrup

Stoptussin or Sinekod

Stoptussin is an antitussive drug with mucolytic and anti-inflammatory effects. It is used in the complex treatment of respiratory diseases, has a lower price and a lower likelihood of contraindications.

Stoptussin - an affordable cough remedy

The disadvantage of the remedy is that it cannot be taken by infants. The medicine is approved for children from one year and older.

Sinekod or Codelac

Codelac is a generic of Sinekod, characterized by a low price, similar forms of release and similar contraindications. The remedy is used for bronchitis, laryngitis, bronchial asthma and other diseases of the DP.

Despite the same dosage of funds, taking Codelac is more often accompanied by side effects.

Codelac is similar in composition to Sinekod

Tussicod or Sinekod

Tussicode is a Belarusian analogue of Sinekod, used for dry cough for various indications. This drug is not available in Russian pharmacies. Sinekod acts faster, less often causes dizziness and drowsiness, and is also approved for use in infants.

The only advantage of Tussikoda is its low price.

Tussikod is produced in Belarus

Sinekod or Ascoril

Ascoril is a multifunctional drug in the form of a syrup, used for both dry and productive coughs. It accelerates the liquefaction of sputum and accelerates its outflow, relieves inflammation, and also stops coughing.

Ascoril - expectorant

This remedy has more adverse reactions and is less effective against unproductive coughs. But for the treatment of respiratory diseases and getting rid of sputum, this is the best option.

Erespal or Sinekod

Erespal is a complex drug used to suppress cough and treat respiratory diseases. It helps to get rid of not only the cough reflex, but also the cause of its appearance. Used for dry and wet coughs.

The disadvantages of Erespal are frequent allergic reactions to the drug, problems with the digestive and cardiovascular systems while taking it, as well as the inability to use children under 2 years of age.

Erespal - a complex cough remedy

Sinekod or Broncholitin

Bronholitin is a herbal remedy with an alkaloid in the composition, which relieves hysterical cough due to the expansion of the bronchi and inhibition of the cough center. In terms of speed of action, the drugs are approximately equal.

Broncholitin - plant-based syrup

The disadvantage of Bronholitin is its high toxicity. It is strictly forbidden to exceed the recommended dose of this drug.

Lazolvan or Sinekod

Lazolvan is a mucolytic drug. Unlike Sinekod, it does not suppress cough, but helps to thin and eliminate sputum from the bronchi. Lazolvan is used only for a wet cough, while Sinekod only helps with a dry one.

These are drugs with different effects, so it is not correct to compare them.

Lazolvan removes sputum from the bronchi

Young mothers know firsthand what it is like not to sleep at night when the child is sick and coughs like a real smoker. With a weakened immune system, a common cold can develop into pharyngitis, tonsillitis and bronchitis. What to do if the infection has reached the bronchi, and the baby cannot cope with the cough on his own? Synekod for children will help stop bouts of hysterical cough and remove infected sputum from the bronchi.

Sinekod is a mucolytic drug of a new generation, whose action is based on blocking the area of the brain responsible for the cough reflex, increasing the lumen of the bronchi and thinning the sputum. Before using the drug, it is necessary to consult a pediatrician, read the instructions and determine the dosage. Sinekod is a drug that is sold in the pharmacy network without a doctor's prescription.

Sinekod is used to relieve cough symptoms and improve respiratory function in children from 2 months of age. For ease of use, Sinekod is produced in the following forms:

syrup;
drops;
pills;
solution ampoules.

Syrup and drops are used to treat cough in children, tablets and syrup are suitable for adults. The manufacturer of the drug is Novartis Consumer Health S.A. (Switzerland), specializing in the production of drugs for the treatment of the respiratory system.

The syrup does not contain sugar, sorbitol and saccharin are used as a sweetener, so it can be used to treat children with obesity and diabetes. Packaged there is a dark glass bottle with a volume of 100 and 200 ml, a measuring container, instructions for use. Syrup is a clear liquid with vanilla flavor. The syrup is indicated for use in children from 3 years of age.

Sinekod drops are produced in a dark glass bottle of 10 and 20 ml. It is specially designed for infants and is indicated for use by babies from 6 months and older. The package contains drops, instructions for use. Sinekod tablets are indicated for use by adolescents over 12 years of age.

The mechanism of action of the drug

Sinekod is used to treat dry hysterical cough of various origins. Improves sputum discharge, expands the lumen of the bronchi, stops coughing attacks. Indications for the use of the drug Sinekod are respiratory diseases in children:

whooping cough;
bronchitis;
pharyngitis;
chemical burn of the nasopharynx;
cough provoked by surgery;
other inflammatory diseases of the bronchopulmonary system: influenza, laryngitis, SARS.

The active substance is butamirate, which acts purposefully on the cough center in the brain. It relieves inflammation, blocks coughing attacks, expands the bronchi, improves breathing. Rapidly absorbed in the intestine, excreted by the kidneys in the form of metabolites.

Sinekod drops and syrup should be combined with antibacterial therapy (antibiotic treatment) and physiotherapy procedures (inhalations, ultraviolet irradiation, and others).

Dosage and method of application

Depending on the age of the child is prescribed:

drops - for children from 2 months to 3 years;
syrup - for babies aged 3 years and older;
tablets - for adolescents from 12 years old;
ampoules with intravenous solution are prescribed only for adults.

It is necessary to use Sinekod for children only after the recommendation of a pediatrician; self-medication is not allowed. The doctor will take into account the characteristics of the baby, the ability to respond to medications, the degree of damage to the respiratory system and make the correct diagnosis. Improper treatment can lead to complications, suffocation, pneumonia.

Dry cough can be due to allergies, swelling of the airways, which is a dangerous condition. The doctor will determine the nature of the disease: obstructive, bacterial, caused by physical impact or foreign objects entering the respiratory system. Sinekod should not be drunk immediately, as soon as the baby coughs hysterically when liquid or food enters the respiratory system.

Drops and syrup Sinekod prescribed for prolonged prolonged cough without visible signs of improvement in the bacterial, viral nature of the disease with signs of inflammation.

The following norms for taking the drug in the form of a syrup are established:

age 3-5 years - 5 ml before meals 3 r per day;
6-12 years - 10 ml before meals 3 times a day;
adolescents from 12 years old - 15 ml 3 r per day.

Drops are intended for infants and children older than 1 year to 3:

babies 2 months of age up to a year - before feeding 4 r per day, 10 drops each;
children from 1 to 3 years old - 15 drops 4 r per day;
children from 3 years old take 25 drops 4 r per day.

For the treatment of infants, drops are diluted with warm boiled water. A small child should not be left unattended for a long time - the passing sputum can make it difficult to breathe. After taking the medicine, you need to put the little one on the barrel or keep it upright.

When coughing with sputum, you need to tilt the baby forward, tap on the back or massage.

Contraindications and side effects

Instructions for use of the drug clearly indicate diseases and conditions in which Sinekod should not be used. First of all, it is a high sensitivity to the components of the drug and allergies. Sinekod refers to herbal medicines, so it is recommended to do an allergy test before taking it. Especially relevant is the requirement before treating young children, whose body is unpredictable.

After taking the medicine, unpleasant consequences are also possible, especially in infants:
irritation, redness, rash on the skin, accompanied by itching;

nausea;
vomit;
dizziness;
headache;
fatigue, weakness.

If symptoms are present, stop taking the drug and seek medical attention. To stop the symptoms of allergies, you should take antihistamines (Fenistil, Suprastin, Diazolin).

Bronchopulmonary diseases in children are the most common disease that occurs for various reasons. Most often, these are colds of a bacterial and viral nature, which are sometimes difficult to treat with antibiotics and general therapy.

Non-narcotic antitussives.

Composition of Sinekod

Active substance:

butamirate citrate 5 mg/ml.

Manufacturers

Novartis Consumer Health S.A. (Switzerland)

pharmachologic effect

pharmacological properties.

Butamirat. the active substance of the drug is an antitussive agent of central action.

It does not belong to opium alkaloids either chemically or pharmacologically.

Suppresses cough, having a direct effect on the cough center.

It has a bronchodilating effect (expands the bronchi).

Helps facilitate breathing by improving spirometry (reduces airway resistance) and blood oxygenation (oxygenates the blood).

Pharmacokinetics.

Butamirate is rapidly and completely absorbed when taken orally.

After taking 150 mg of butamirate, the maximum plasma concentration of the main metabolite (2-phenylbutyric acid) is reached after about 1.5 hours and is 3.4 μg / ml.

With repeated administration of the drug, its concentration in the blood remains linear and cumulation is not observed.

Hydrolysis of butamirate:

initially to 2-phenylbutyric acid and diethylaminoethoxyethanol,
starts in the blood.

These metabolites also have antitussive activity.

Like butamirate, metabolites have an almost maximum (about 95%) degree of binding to plasma proteins, which causes, among other things, their long plasma half-life.

Metabolites are excreted mainly by the kidneys, with acidic metabolites being largely bound to glucuronic acid.

The half-life is 6 hours.

Side effects of Sinekod

From the side of the central nervous system:

drowsiness,
dizziness.

From the gastrointestinal tract:

nausea,
diarrhea.

From the side of the skin:

exanthema.

Rarely, allergic reactions may develop.

Indications for use

Symptomatic treatment of dry cough of various etiologies:

cough in the preoperative and postoperative period,
during surgical procedures,
bronchoscopy,
with whooping cough.

Contraindications Sinekod

Hypersensitivity to the components of the drug, children under 2 months of age, pregnancy (I trimester), lactation.

Method of application and dosage

Inside, before eating.

Children from 3 to 6 years old - 5 ml 3 times a day; from 6 to 12 years - 10 ml 3 times a day; 12 years and older - 15 ml 3 times a day; adults - 15 ml 4 times a day.

Use a measuring cap.

The measuring cap should be washed and dried after each use.

If the cough persists for more than 7 days, you should consult a doctor.

Overdose

Symptoms:

drowsiness,
nausea,
vomiting,
diarrhea,
dizziness and low blood pressure.

Treatment:

gastric lavage: intake of activated charcoal: maintenance of vital body functions.

There is no specific antidote.

Interaction

No drug interactions have been reported for butamirate.

special instructions

Carefully.

Pregnancy (II and III trimesters).

Use during pregnancy and lactation.

In studies conducted in animals, no adverse effects on the fetus were noted.

Controlled studies in pregnant women have not been conducted.

In this regard, the drug should not be used in the first trimester of pregnancy.

In the II and III trimesters, the use of the drug is possible, taking into account the benefits to the mother and the potential risk to the fetus.

Given the lack of data on the excretion of butamirate with breast milk:

the appointment of the drug during lactation is not recommended.

Due to the fact that butamirate suppresses the cough reflex, the simultaneous use of expectorants should be avoided in order to avoid accumulation of sputum in the respiratory tract with the risk of developing bronchospasm and respiratory tract infection.

The syrup contains saccharinate and sorbitol as sweeteners, so it can be prescribed to patients with diabetes mellitus.

Influence on the ability to drive vehicles or mechanisms.

The drug can cause drowsiness, so care should be taken when driving vehicles and when performing work that requires concentration (for example, when working with mechanisms) after taking the drug.